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Down Syndrome Research Foundation

We are a UK Registered Charity with International Links and a objective to improve the outcome for all people born with Trisomy 21 (T21) which is the cause of Down syndrome (DS), and the most common cause (at birth) of learning disability (mental handicap).

Trisomy 21 happens at conception. About 1 in 400 babies are conceived with three copies of chromosome 21. Read more about T21 in the FAQ section. People with T21 have very full, happy and active lives but most have some form of intellectual disability and increased rates of congenital and some acquired conditions.

For many years scientists believed that it was impossible to do anything to treat or intervene medically to lessen the effects of T21 in the person's health and wellbeing. The main reason for this was the fact that there are over 500 genes on chromosome 21. However exciting advances within the last 10 years have linked particular genes and biochemical pathways to the particular problems seen in T21.

Who to contact

Contact Name
Down Syndrome Reasearch Foundation

Where to go

42 Cleveland Gardens
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